Xiaofeng Huang

This study generates hypoimmunogenic gastric insulin-secreting organoids (GINS) and shows PD-L1 engineering improves their survival under immune challenge.

This study identifies SP5 and SP8 as transcription factors that drive primary cilia formation through genetic and transcriptomic analyses in mouse embryos.

The paper identifies MTA2 and SATB2 as a chromatin complex that maintains colonic identity by retaining HNF4A on colonic chromatin, preventing plasticity toward small intestine.