Author

Yinwen Liang

Memorial Sloan Kettering Cancer CenterORCID 0000-0002-9945-3768Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Alexandra L. JoyneriD· 3 shared Daniel N. StepheniD· 3 shared Salsabiel El NagariD· 2 shared Zhimin LaoiD· 2 shared Anna‐Katerina HadjantonakisiD· 1 shared Francisco Pereira LoboiD· 1 shared Kathryn V. AndersoniD· 1 shared Mark W. L. KennedyiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCancer Biology

Alexandra L. JoynerORCID

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3 papers

Recent·Most cited

A Rare Nestin-Expressing Granule Cell Precursor Subpopulation Underlies SHH Medulloblastoma Formation

Salsabiel El Nagar, Yinwen Liang, Daniel N. Stephen, Synphen H. Wu, Alexandra L. Joyner

The paper identifies a rare Nestin-expressing granule cell precursor subpopulation that drives SHH medulloblastoma formation with high tumorigenic efficiency.

bioRxiv · May 26, 2026 · PreprintCancer Biology

Transcription factors SP5 and SP8 drive primary cilia formation

Yinwen Liang, Richard P. Koche, Ravindra B. Chalamalasetty, Daniel N. Stephen, Mark W. L. Kennedy, Zhimin Lao, Yunong Pang, Ying-Yi Kuo, Moonsup Lee, Francisco Pereira Lobo, Xiaofeng Huang, Anna‐Katerina Hadjantonakis, Terry P. Yamaguchi, Kathryn V. Anderson, Alexandra L. Joyner

This study identifies SP5 and SP8 as transcription factors that drive primary cilia formation through genetic and transcriptomic analyses in mouse embryos.

Science · Aug 28, 2025Peer-reviewedDevelopmental Biology

PTEN restrains SHH medulloblastma growth through cell autonomous and nonautonomous mechanisms

Zhimin Lao, Salsabiel El Nagar, Yinwen Liang, Daniel N. Stephen, Alexandra L. Joyner

This study shows that PTEN loss accelerates SHH medulloblastoma growth through both cell-autonomous and nonautonomous mechanisms in mouse models.

bioRxiv · Jul 31, 2025 · PreprintCancer Biology