Author

Eleni G. Christodoulou

National University of SingaporeORCID 0000-0002-9209-8425Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:Ribo-seq· 1

Frequent Co-Authors

Owen J. L. RackhamiD· 2 shared Anissa Anindya WidjajaiD· 1 shared Benjamin L. GeorgeiD· 1 shared Chee Jian PuaiD· 1 shared Chi Wai Eric SoiD· 1 shared Elaine Yiqun CaoiD· 1 shared Eleonora AdamiiD· 1 shared Enrico G. PetrettoiD· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersGenomics

Owen J. L. RackhamORCID

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2 papers

Recent·Most cited

Translational control of cardiac fibrosis

Sonia Pankaj Chothani, Sebastian Schäfer, Eleonora Adami, Sivakumar Viswanathan, Anissa Anindya Widjaja, Sarah R. Langley, Jessie Tan, Mao Wang, Nicholas M. Quaife, Chee Jian Pua, Giuseppe Alessandro D’Agostino, Shamini Guna Shekeran, Benjamin L. George, Stella Lim, Elaine Yiqun Cao, , Owen J. L. Rackham

The paper identifies translational regulators of fibrogenic genes in human cardiac fibroblasts and shows their role in cardiac fibrosis through ribosome profiling and RNA-binding protein analysis.

Circulation · Jul 9, 2019Peer-reviewedGenomics

Identification of drugs for leukaemia differentiation therapy by network pharmacology

Eleni G. Christodoulou, Lin Ming Lee, Kian Leong Lee, Tsz Kan Fung, Chi Wai Eric So, Enrico G. Petretto, S. Tiong Ong, Owen J. L. Rackham

The paper identifies drugs for leukaemia differentiation therapy using network pharmacology, finding that dimaprit and mebendazole enhance ATRA-mediated differentiation in leukaemia cells.

bioRxiv · Jul 5, 2019 · PreprintSystems Biology