Author

Chun Zhou

Sir Run Run Shaw HospitalORCID 0000-0002-9257-468XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

Caiqiao ZhangiD· 1 shared Chao JiangiD· 1 shared Chen YeiD· 1 shared Guoping ZhaoiD· 1 shared Hao Wang· 1 shared Hui CheniD· 1 shared Jie Gao· 1 shared Jizhong LouiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

Caiqiao ZhangORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintMay 22, 2026

PD-1 remodels SHP2 dynamics and drives the non-catalytic inhibition of T cell activation

Panyu Fei, Peng Jiao, Jie Gao…·Wei Chen

This study reveals that PD-1 remodels SHP2 dynamics to inhibit T cell activation through a non-catalytic mechanism, independent of its phosphatase activity.

2 citations

humanstructural biology

𝕏 PostBluesky

BiochemistryeLifePeer-reviewedMar 13, 2024

Bacterial exonuclease III expands its enzymatic activities on single-stranded DNA

Hao Wang, Chen Ye, Qi Lu…·Yan Li

This study shows bacterial ExoIII can cleave single-stranded DNA (ssDNA) via exonuclease and endonuclease activities, revealing new enzymatic functions and implications for biosensor design.

11 citations

E. coliDNA methylation

𝕏 PostBluesky