Endogenous and fluorescent sterols reveal the molecular basis for ligand selectivity of human sterol transporters
Laura Depta, Hogan P. Bryce-Rogers, Nienke J Dekker, Anna Wiehl Bønke, Nicolo' Camporese, Mingxing Qian, Yuanjian Xu, Douglas F. Covey, Luca Laraia
The paper profiles fluorescent steroid probes across ten STPs to uncover selectivity differences and establishes a screening panel to identify new Aster-B inhibitors.
Journal of Lipid Research · Dec 31, 2024Peer-reviewedBiochemistry