Author

Laura Depta

Technical University of DenmarkORCID 0000-0002-4076-7316Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Douglas F. CoveyiD· 2 shared Hogan P. Bryce-RogersiD· 2 shared Luca LaraiaiD· 2 shared Yuanjian Xu· 2 shared Amanda Therese Pauli· 1 shared Anna Wiehl Bønke· 1 shared Daniel RauhiD· 1 shared Daniel WüstneriD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBiophysics

Douglas F. CoveyORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Selective covalent-allosteric tools to dissect Akt2

Lena Quambusch, Giovanni Danilo D’Angelo, Tonia Kirschner, Maria Beerbaum, Laura Depta, Fabian Schnecke, Janina Niggenaber, Sven Brandherm, Jörn Weisner, Matthias Philipp Müller, Leif Dehmelt, Daniel Rauh

This study develops Akt2-selective covalent-allosteric probes for functional studies and mechanistic insights into Akt2's role in health and disease.

bioRxiv · Jun 19, 2026 · PreprintCancer Biology

The orientation of cholesterol's hydroxyl group affects its membrane dynamics and intracellular transport

Line Lauritsen, Amanda Therese Pauli, Miklas P.W. Larsen, Peter Reinholdt, Holger A. Scheidt, Yuanjian Xu, Douglas F. Covey, Laura Depta, Hogan P. Bryce-Rogers, Luca Laraia, Jacob Kongsted, Daniel Wüstner

This study shows that the orientation of cholesterol's hydroxyl group affects membrane dynamics and intracellular transport in human astrocytes.

bioRxiv · Feb 4, 2026 · PreprintBiophysics

Endogenous and fluorescent sterols reveal the molecular basis for ligand selectivity of human sterol transporters

Laura Depta, Hogan P. Bryce-Rogers, Nienke J Dekker, Anna Wiehl Bønke, Nicolo' Camporese, Mingxing Qian, Yuanjian Xu, Douglas F. Covey, Luca Laraia

The paper profiles fluorescent steroid probes across ten STPs to uncover selectivity differences and establishes a screening panel to identify new Aster-B inhibitors.

Journal of Lipid Research · Dec 31, 2024Peer-reviewedBiochemistry