Oren Rom

This study shows EHD1 promotes inflammation and stabilizes sortilin in macrophages, accelerating atherosclerosis through enhanced TNFR2-NF-kB signaling and endocytic recycling.

This study shows fibronectin-binding integrins drive ER stress in endothelial cells under atherogenic conditions, promoting inflammation through JNK-c-Jun signaling.

This study investigates how RvD1 reduces inflammation, cell death, and fibrosis in MASH by targeting Stat1, ER stress, and MMP pathways.

The paper identifies loss-of-function variants affecting liver-related blood traits that reduce CVD risk without increasing metabolic disease risk, highlighting potential therapeutic targets.