Fanglin Ma

Macrophage EHD1 promotes inflammation and stabilizes sortilin to accelerate atherosclerosis

This study shows EHD1 promotes inflammation and stabilizes sortilin in macrophages, accelerating atherosclerosis through enhanced TNFR2-NF-kB signaling and endocytic recycling.

Targeting ZNRF3 and RNF43 to Restore Regeneration and Reverse Metabolic Dysfunction-Associated Steatotic Liver Disease

This study shows that deleting ZNRF3 and RNF43 in hepatocytes after MASH onset restores liver regeneration and reverses steatosis, inflammation, and fibrosis without causing tumorigenesis or hepatotoxicity.

Therapeutic Activity of Resolvin D1 (RvD1) in Murine MASH

This study investigates how RvD1 reduces inflammation, cell death, and fibrosis in MASH by targeting Stat1, ER stress, and MMP pathways.

The pluripotency factor Tex10 finetunes Wnt signaling for PGC and male germline development

This study identifies Tex10 as a regulator of Wnt signaling in PGC specification and male germline development using mouse models and single-cell RNA sequencing.