Author

Blythe Irwin

University of WashingtonORCID 0000-0002-9273-7100Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:mouse· 1

Frequent Co-Authors

Hao Yuan KuehiD· 2 shared Kenneth K.H. NgiD· 2 shared Arnav MehtaiD· 1 shared Ellen V. RothenbergiD· 1 shared Mary A. YuiiD· 1 shared Michael B. ElowitziD· 1 shared Nicholas A. PeaseiD· 1 shared Phuc Hong NguyeniD· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersSystems Biology

Hao Yuan KuehORCID

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2 papers

Recent·Most cited

Temporal scaling in developmental gene networks by epigenetic timing control

Phuc Hong Nguyen, Nicholas A. Pease, Kenneth K.H. Ng, Blythe Irwin, Hao Yuan Kueh

The paper identifies an epigenetic timer mechanism that controls temporal scaling in developmental gene networks, enabling flexible size control through delayed activation of key regulators.

bioRxiv · Sep 5, 2019 · PreprintSystems Biology

A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment

Kenneth K.H. Ng, Mary A. Yui, Arnav Mehta, Sharmayne Siu, Blythe Irwin, Shirley Pease, Satoshi Hirose, Michael B. Elowitz, Ellen V. Rothenberg, Hao Yuan Kueh

The paper shows that stochastic cis-acting events at the Bcl11b locus control T-cell lineage commitment dynamics through a delay in gene activation.

eLife · Nov 12, 2018Peer-reviewedBioinformatics