Author

Xingyu Chen

Cedars-Sinai Medical CenterORCID 0000-0002-9284-4950Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xingyu Chen3 papers · Institute of Vegetables and Flowers

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:eQTL / molecular QTL mapping· 1 Research Focus:GWAS / association mapping· 1 Assay:metabolomics· 1

Frequent Co-Authors

Aaron S. HoweiD· 1 shared Billie Au· 1 shared Bipul R. AcharyaiD· 1 shared Boopathi SubramaniyaniD· 1 shared Chen CaoiD· 1 shared Corazon Gutierrez· 1 shared Dan TheodorescuiD· 1 shared Deshan PereraiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenetics

Aaron S. HoweORCID

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2 papers

Recent·Most cited

Loss of the Y chromosome drives cancer metabolic reprogramming

Boopathi Subramaniyan, Bipul R. Acharya, Prince Anand, Saravana Kumar Kailasam Mani, Saswat Mohapatra, Xingyu Chen, Fangyuan Qu, Yesai S. Fstkchyan, Corazon Gutierrez, Hany A. Abdel-Hafiz, James C. Costello, Dan Theodorescu

The paper shows that loss of the Y chromosome in bladder cancer drives metabolic reprogramming through DDR2, enhancing glycolysis and tumor aggressiveness.

bioRxiv · Aug 26, 2025 · PreprintCancer Biology

Statistical model integrating interactions into genotype-phenotype association mapping: an application to reveal 3D-genetic basis underlying Autism

Qing Li, Chen Cao, Deshan Perera, Jingni He, Xingyu Chen, Feeha Azeem, Aaron S. Howe, Billie Au, Jun Yi Yan, Quan Long

The paper introduces ILMM, a statistical model that integrates genetic interactions into genotype-phenotype association mapping, revealing 3D-genetic basis of ASD and 3D-eQTLs using whole genome and transcriptome sequencing data.

bioRxiv · Jul 27, 2020 · PreprintGenetics