Author
University of CambridgeORCID 0000-0002-9300-497XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
De‐Sheng Ker, Hedaya Aboalnaga, Luca Pellegrini
The paper presents a method for high-resolution cryoEM of nucleosomes in mammalian cell nuclear extracts without requiring thin sectioning.
Luay I. Joudeh, Robert E Appleby, Joseph D Maman, Luca Pellegrini
The paper presents the cryoEM structure of a RAD51 displacement loop, revealing the mechanism of strand exchange during homologous recombination.
Zhan Yin, Mairi Louise Kilkenny, De‐Sheng Ker, Luca Pellegrini
This study uses cryoEM to capture the conformational changes of the human primosome during RNA primer synthesis, revealing how primase and polymerase subunits coordinate primer synthesis and termination.
Letícia Koch Lerner, Sandro Holzer, Mairi Louise Kilkenny…·Julian E. Sale
The paper identifies a G quadruplex binding domain in Timeless and shows its collaboration with DDX11 to process G4 structures during DNA replication.