Author

Letícia Koch Lerner

MRC Laboratory of Molecular BiologyORCID 0000-0003-3476-5231Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:DNA methylation· 1 Organism:human· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Julian E. SaleiD· 2 shared Pierre MuratiD· 2 shared Alice BittlestoniD· 1 shared Dana BranzeiiD· 1 shared Davide Schiavone· 1 shared Guillaume GuilbaudiD· 1 shared Helen S. Wilkes· 1 shared Joseph D Maman· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenomics

Julian E. SaleORCID

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2 papers

Recent·Most cited

GenomicsNucleic Acids ResearchPeer-reviewedJul 8, 2022

Determination of human DNA replication origin position and efficiency reveals principles of initiation zone organisation

Guillaume Guilbaud, Pierre Murat, Helen S. Wilkes…·Torsten Krude

The paper maps human DNA replication origins and their efficiency, showing hierarchical organization within initiation zones.

66 citationstop 3%

humanwhole-genome sequencing

𝕏 PostBluesky

Molecular BiologybioRxivPreprintOct 31, 2019

Timeless couples G quadruplex detection with processing by DDX11 during DNA replication

Letícia Koch Lerner, Sandro Holzer, Mairi Louise Kilkenny…·Julian E. Sale

The paper identifies a G quadruplex binding domain in Timeless and shows its collaboration with DDX11 to process G4 structures during DNA replication.

DOI 10.1101/826578

DNA methylationexperimental assay

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