Antigenic cancer persister cells survive direct T cell attack
Michael Wang, Brandon E. Mauch, August Finley Williams, Tania Barazande-Pour, Filipe Araujo Hoffmann, Sophie H. Harris, Cooper P. Lathrop, Claire E. Turkal, Bryan S. Yung, Michelle H. Paw, David A. G. Gervasio, Tiffany Tran, Anna E. Stuhlfire, Theresa W. Guo, Gregory A. Daniels, , Matthew J. Hangauer
The paper identifies antigenic cancer persister cells that survive direct T cell attack by leveraging apoptosis to avoid inflammatory death and acquiring mutations for immune resistance.
bioRxiv · Mar 14, 2025 · PreprintCancer Biology