Joana Almaça

This study shows hIAPP aggregation disrupts islet microvascular stability by downregulating EC genes and causing pericyte detachment, impairing vasomotor responses.

This study shows that pericyte dysfunction in pancreatic islets leads to vascular abnormalities and inflammation before diabetes onset in mice treated with streptozotocin.

The paper shows pancreatic islets communicate with the brain via vagal sensory neurons that respond to serotonin released from beta cells.