Author

Iryna Zherka

University of OxfordORCID 0000-0002-9341-352XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Amato J. GiacciaiD· 1 shared Dhanya K. NambiariD· 1 shared Dominika Majorova· 1 shared Edward Elliot GravesiD· 1 shared Heather Clark· 1 shared Ian J. ChaiiD· 1 shared Kerriann M. CaseyiD· 1 shared Monica M. OlcinaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Amato J. GiacciaORCID

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1 paper

Recent·Most cited

Targeting C5aR1 Reveals Protective Macrophage Maturation States in Intestinal Injury

Heather Clark, Ian J. Chai, Stavros Melemenidis, Dhanya K. Nambiar, Ryan K. Kim, Yanyan Jiang, Kerriann M. Casey, Iryna Zherka, Dominika Majorova, Trent M. Woodruff, Edward Elliot Graves, Quynh‐Thu Le, Simon J. A. Buczacki, Amato J. Giaccia, Monica M. Olcina

This study shows targeting C5aR1 reduces radiation-induced intestinal injury by promoting macrophage phenotypes that decrease stem cell apoptosis and improve tumor response.

bioRxiv · Nov 11, 2025 · PreprintImmunology