Kerriann M. Casey

This study identifies arginine as a key amino acid for achieving optical transparency in tissues through its ultraviolet absorption and refractive index modulation properties.

This study shows FLASH radiotherapy reduces radiation-induced mucositis in a mouse model of Fanconi anemia compared to conventional radiotherapy.

This study shows targeting C5aR1 reduces radiation-induced intestinal injury by promoting macrophage phenotypes that decrease stem cell apoptosis and improve tumor response.

This paper introduces a color-neutral and reversible tissue transparency method that enables longitudinal deep-tissue imaging in live mice with high spatiotemporal resolution.

This study compares FLASH and conventional dose rate radiotherapy in a murine breast cancer model, finding comparable tumor control with FLASH achieving higher eradication rates at 30 Gy in small tumors.

This paper discovers a broad-spectrum, non-toxic polymer virucide effective against multiple viruses at nanomolar concentrations, showing efficacy in a murine RSV model.

This paper introduces an electrolytic lesioning technique compatible with neuroelectrophysiology recordings, enabling precise brain lesioning without disrupting electrophysiological measurements.

This study shows that Xist ribonucleoprotein complexes drive sex-biased autoimmunity in males, leading to autoimmune pathology and reprogramming of immune cells to resemble female patterns.

The paper investigates the evolutionary retention of ribosomal protein paralogs eS27 and eS27L by showing their subfunctionalized expression patterns are necessary for maintaining total protein expression across cell types.

Portal integrates large-scale single-cell datasets efficiently and accurately by preserving biological variation across samples, platforms, and species.

The paper creates a comprehensive cell atlas of mouse lemurs using single-cell RNA sequencing, identifying over 750 cell types and comparing their molecular profiles to humans, mice, and macaques.

This study analyzes epigenomic and transcriptomic changes across mouse tissues with age, identifying age-related immune pathway activation and retroviral sequence upregulation.