NeurosciencebioRxivPreprint
ERβ mediates sex-specific protection in the App-NL-G-F mouse model of Alzheimer's disease
Aphrodite Demetriou, Birgitta Lindqvist, Heba G. Ali…·Ivan Nalvarte
This study investigates ERβ's role in sex-specific protection against AD pathology in AppNL-G-F mice, finding ERβ activation protects both males and females, with ovariectomy increasing Aβ levels but limited overall pathology effects.
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