Author

Lisa Bucher

University of ZurichORCID 0000-0002-9346-7915Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Andrew S. BelmontiD· 1 shared Falko NoéiD· 1 shared Gabriel E. NeurohriD· 1 shared Kaivalya WalavalkariD· 1 shared Letizia ManfrediiD· 1 shared Matthias AltmeyeriD· 1 shared Raffaella SantoroiD· 1 shared Sandhya ManohariD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCell Biology

Andrew S. BelmontORCID

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1 paper

Recent·Most cited

Rewired mRNA homeostasis enforces cell-size associated senescence

Letizia Manfredi, Kaivalya Walavalkar, Shreyasi Neogi, Lisa Bucher, Falko Noé, Gabriel E. Neurohr, Raffaella Santoro, Andrew S. Belmont, Matthias Altmeyer, Sandhya Manohar

This study shows that excess cell size drives senescence by altering mRNA homeostasis and reorganizing the genome, leading to the secretory phenotype and cell cycle arrest.

bioRxiv · Oct 22, 2026 · PreprintCell Biology