Molecular BiologybioRxivPreprint
Specialization of ubiquitin ligases to distinct nucleic acid sensors
Ibrahim Syed, Sheng Chen, David J. Peeler…·Daniel Gonçalves-Carneiro
The paper identifies how SPRY domains in ubiquitin ligases recognize nucleic acid sensors, using AlphaFold to discover novel interactions and their implications for RNA vaccine design.
DOI 10.1101/2025.10.01.678329