Author

Marco Antonio Briones-Orta

Imperial College LondonORCID 0000-0001-6627-1901Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Robin J. ShattockiD· 3 shared David J. PeeleriD· 2 shared Paul F. McKayiD· 2 shared Andrew B. WardiD· 1 shared Daniel Gonçalves-CarneiroiD· 1 shared Daniel ReumanniD· 1 shared Dinh Chuong NguyeniD· 1 shared Fabian MulderiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersImmunology

Robin J. ShattockORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 18, 2026

Spatiotemporal control of STING activation and saRNA delivery decouples humoral and cellular immunity

David J. Peeler, Ziyin Wang, Livia Spiga…·John S. Tregoning

This study shows that timing and location of STING activation relative to saRNA delivery affects humoral and cellular immune responses, with synchronized delivery enhancing T cell responses without impacting antibody production.

DOI 10.64898/2026.09.11.751026

experimental assaydrug response / drug discovery

𝕏 PostBluesky

ImmunologybioRxivPreprintAug 26, 2026

Consensus native-like hepatitis C virus E1E2 engages broadly neutralizing antibody precursors

Fabian Mulder, Fabien Cannac, Joan Capella-Pujol…·Kwinten Sliepen

This paper develops a consensus HCV E1E2 antigen that engages germline B cell precursors of broadly neutralizing antibodies.

DOI 10.64898/2026.08.25.746952

humanproteomics

𝕏 PostBluesky

Molecular BiologybioRxivPreprintOct 1, 2025

Specialization of ubiquitin ligases to distinct nucleic acid sensors

Ibrahim Syed, Sheng Chen, David J. Peeler…·Daniel Gonçalves-Carneiro

The paper identifies how SPRY domains in ubiquitin ligases recognize nucleic acid sensors, using AlphaFold to discover novel interactions and their implications for RNA vaccine design.

DOI 10.1101/2025.10.01.678329

humanproteomics

𝕏 PostBluesky