Ilan Lampl

Inherent coupling of perceptual judgments to actions in the mouse cortex

This study shows that perceptual judgments in mice are coupled to actions in the premotor cortex, with some cells encoding block identity during a vibrotactile detection task.

Isolated correlates of somatosensory perception in the mouse posterior cortex

This study identifies cortical regions in mice associated with somatosensory perception independent of perceptual report by comparing two task conditions.

A novel theoretical framework for simultaneous measurement of excitatory and inhibitory conductances

This paper introduces a method to simultaneously measure excitatory and inhibitory conductances in neurons using current clamp recordings and sinusoidal current injection.

Localized Chemogenetic Silencing of Inhibitory Neurons: A novel Mouse Model of Focal Cortical Seizures

This paper introduces a novel mouse model of focal cortical seizures using chemogenetic inhibition of GABAergic neurons, showing reliable induction of seizures with characteristics similar to human epilepsy.

Multiple timescales account for adaptive responses across sensory cortices

The paper shows that adaptive responses in visual, somatosensory, and auditory cortices follow similar patterns across different sensory modalities.

Stereotactic system for accurately targeting deep brain structures in awake head-fixed mice

The paper introduces a stereotactic system for accurately targeting deep brain structures in awake head-fixed mice, validated through electrophysiological recordings and histological reconstruction.

Principles for simultaneous measurement of excitatory and inhibitory conductances of single cells in a single trial

The paper introduces a method to simultaneously measure excitatory and inhibitory conductances in single neurons during a single trial using sinusoidal current injection and optimization algorithms.

The correlated state in balanced neuronal networks

The paper shows that correlated feedforward input increases correlations in balanced neuronal networks, leading to a correlated state with excitatory-inhibitory balance similar to in vivo recordings.

Membrane potential correlates of network decorrelation and improved SNR by cholinergic activation in the somatosensory cortex.

This study shows cholinergic activation reduces correlated spontaneous synaptic fluctuations and improves sensory response SNR in the somatosensory cortex.

High-efficiency optogenetic silencing with soma-targeted anion-conducting channelrhodopsins

This paper improves optogenetic silencing by enhancing membrane targeting and subcellular compartmentalization of GtACRs, resulting in more efficient neuronal inhibition.

Coupling Of Tactile LFP Signals Between Mouse Cortex And Olfactory Bulb

The paper shows that whisker-evoked LFP signals in the olfactory bulb are linked to activity in the ventro-lateral orbitofrontal cortex via volume conductance.

Local and thalamic origins of ongoing and sensory evoked cortical correlations

The paper investigates the role of thalamic and local inputs in cortical synchronization by optogenetically silencing cortical firing and measuring correlations in anesthetized and awake mice.