Author

Prasanna Channathodiyil

Babraham InstituteORCID 0000-0002-9381-6089Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Jonathan M. HouseleyiD· 2 shared Anne Segonds-PichoniD· 1 shared Kieron MayiD· 1 shared Paul D. SmithiD· 1 shared Simon J. CookiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersMolecular Biology

Jonathan M. HouseleyORCID

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2 papers

Recent·Most cited

DNA replication during acute MEK inhibition drives acquisition of resistance through amplification of the BRAF oncogene

Prasanna Channathodiyil, Kieron May, Anne Segonds-Pichon, Paul D. Smith, Simon J. Cook, Jonathan M. Houseley

The paper shows that DNA replication during MEK inhibition drives BRAF amplification and resistance in COLO205 cells, and that blocking cell cycle entry can suppress resistance.

NAR Cancer · Sep 28, 2022Peer-reviewedMolecular Biology

Glyoxal fixation facilitates transcriptome analysis after antigen staining and cell sorting by flow cytometry

Prasanna Channathodiyil, Jonathan M. Houseley

This paper introduces glyoxal fixation as a method to preserve RNA quality in flow-sorted cells stained for antigens, enabling transcriptome analysis of purified cell populations.

PLoS ONE · Jan 22, 2021Peer-reviewedMolecular Biology