Author

A.-L. Sailer

Universität UlmORCID 0000-0002-9391-4850Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Anita MarchfelderiD· 2 shared Aleksandar CherneviD· 1 shared Alexander EulitziD· 1 shared Dina GrohmanniD· 1 shared Felix GrünbergeriD· 1 shared Felix Neuschütz· 1 shared Henning UrlaubiD· 1 shared J. Brendel· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

Anita MarchfelderORCID

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2 papers

Recent·Most cited

Control of motility and cell shape of Haloferax volcanii is linked by a transcriptional regulator

Phillip Nußbaum, Felix Grünberger, Felix Neuschütz, Kevin Chou, Shamphavi Sivabalasarma, Alexander Eulitz, Anna-Lena Sailer, Katharina Vogl, Marten Exterkate, Wei He, Anita Marchfelder, Dina Grohmann, Sonja‐Verena Albers

This study identifies CsmR as a transcriptional regulator linking motility and cell shape in Haloferax volcanii through transcriptomic analysis and functional experiments.

bioRxiv · Feb 3, 2026 · PreprintMicrobiology

Internal in-frame translation generates Cas11b, which is important for effective interference in an archaeal CRISPR-Cas system

A.-L. Sailer, J. Brendel, Aleksandar Chernev, S. König, Thorsten Bischler, Tom Gräfenhan, Henning Urlaub, Uri Gophna, Anita Marchfelder

The paper identifies Cas11b as an internally translated protein in an archaeal CRISPR-Cas system, showing its necessity for effective interference and Cascade complex formation.

Frontiers in Microbiology · Feb 26, 2025Peer-reviewedMolecular Biology