Johannes Reisert

This study investigates olfactory system degeneration in NPC1 disease using mouse models and human families, finding reduced olfactory sensory neuron density and severe hyposmia in affected individuals.

This study shows that TMEM16B, a Ca2+-activated Cl- channel, influences the response kinetics and action potential generation of olfactory sensory neurons, while the CNG channel primarily determines response delay and adaptation.

This study shows that short-term consumption of ultra-processed semi-synthetic diets impairs olfactory function and brain metabolism in mice.

This study quantifies how trigeminal agonists modulate olfactory responses by measuring Ca2+ changes and EOG responses in mice, showing that trigeminal activation reduces olfactory signal strength.

This paper creates a 3D spatial transcriptomics atlas of the mouse olfactory mucosa, revealing spatial gene distribution patterns and supporting the chromatographic theory of olfaction.

This study shows that insulin promotes the maturation of newly generated olfactory sensory neurons after injury, with a critical time window of days 8-13 post-injury.

The paper shows that Cl- efflux, not Na+ influx, provides a more reliable and robust signal amplification mechanism in vertebrate olfactory receptor neurons.