The UBR box E3 ligases Poe and Hyd are required for efficient Pericentrin degradation
Ramya Varadarajan, Brian J. Galletta, Carey J. Fagerstrom, Karen M. Plevock, Nasser M. Rusan
This study identifies Poe and Hyd as E3 ligases that promote PLP degradation during spermatogenesis, ensuring proper centriole assembly and male fertility.
bioRxiv · Jan 21, 2022 · PreprintDevelopmental Biology