Nasser M. Rusan

This paper shows Xrp1 contributes to genome integrity through p53-dependent DNA damage response and p53-independent cell competition in Drosophila.

This study identifies tumor-associated macrophages as critical for brain metastasis by showing their role in basement membrane remodeling in a Drosophila model.

Autobehaver is an AI pipeline for analyzing Drosophila behavior using video data, identifying key features and classifying behavioral states through a Transformer and XGBoost models.

This study models a MOPD II-associated Pericentrin variant in Drosophila, showing it disrupts dimerization and pericentriolar material recruitment, leading to developmental and cellular defects.

The paper identifies Nup133 and Nup107 as regulators of HTCA development and shows that NPCs recruit dynein to the nuclear envelope to facilitate centriole-nuclear attachment during spermiogenesis.

This study identifies Toga as a regulator that stabilizes sperm head and neck microtubules to maintain axial alignment during spermiogenesis in Drosophila.

The paper identifies genomic regions critical for sperm head-tail connection in Drosophila through a deficiency screen combined with RNAseq analysis.

The paper maps the molecular architecture of the Head-Tail Coupling Apparatus (HTCA) in Drosophila spermiogenesis, revealing its multi-point attachment structure involving the proximal centriole-like (PCL) structure.

This study identifies Poe and Hyd as E3 ligases that promote PLP degradation during spermatogenesis, ensuring proper centriole assembly and male fertility.

The paper shows that Traip function during mitosis is critical for proper brain size in Drosophila, as its loss causes neuronal loss due to mitotic defects.

The paper shows that X and 4th chromosomes are inactivated while Y chromosomes are active in Drosophila primary spermatocytes using single-cell RNA-Seq.

This paper introduces a micro CT method for imaging Drosophila development and disease modeling, showing its utility in studying microcephaly.