Carey J. Fagerstrom

A MOPD II-associated Pericentrin variant disrupts PACT domain dimerization and pericentriolar material recruitment

This study models a MOPD II-associated Pericentrin variant in Drosophila, showing it disrupts dimerization and pericentriolar material recruitment, leading to developmental and cellular defects.

Togaram Ensures Axial Alignment of the Sperm Neck

This study identifies Toga as a regulator that stabilizes sperm head and neck microtubules to maintain axial alignment during spermiogenesis in Drosophila.

The UBR box E3 ligases Poe and Hyd are required for efficient Pericentrin degradation

This study identifies Poe and Hyd as E3 ligases that promote PLP degradation during spermatogenesis, ensuring proper centriole assembly and male fertility.