Ewa Magdalena Goldys

This study develops a light-responsive lipid nanoparticle platform for VEGFA gene editing to suppress choroidal neovascularisation, showing reduced vascular leakage and structural abnormalities in a rat model.

This paper develops a CRISPR-based biosensing system that uses split-trigger activation to amplify Cas12a activity for ultrasensitive molecular detection.

This paper introduces a CRISPR/Cas tandem biosensing system for ultrasensitive DNA detection without pre-amplification, achieving 1 aM sensitivity and distinguishing cancer mutations in CRC mice.

This paper develops an autocatalytic Cas13a biosensor using circular RNA mediators to enable ultrasensitive RNA detection without preamplification.

HyperSeq integrates hyperspectral imaging and transcriptomics on the same cell to link optical spectra with molecular states in MCF-7 breast cancer cells.

This study shows how oocyte-secreted factors alter proteomic and metabolic profiles of oocytes and cumulus cells during maturation, enhancing their cooperativity for fertilization.

This paper develops a deep learning-based method to identify aneuploid cells in mouse embryos using brightfield images, achieving high accuracy in distinguishing euploid and aneuploid cells.

This paper develops a deep learning method called RELIC to differentiate between normal and pathological kidney exfoliated cells using urine samples with 82% accuracy.

This study shows that NAD+ repletion with NMN improves oocyte quality and fertility in aged animals, and enhances IVF success in older mice.