Author

Velayudhan Satheeja Santhi

Icahn School of Medicine at Mount SinaiORCID 0000-0002-9448-2105Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:development & morphogenesis· 2 Organism:Xenopus· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Keiji ItohiD· 3 shared Sergei Y. SokoliD· 3 shared Chih-Wen ChuiD· 2 shared Dominique AlfandariiD· 1 shared Minghui WangiD· 1 shared Mintie PuiD· 1 shared Siu Sylvia LeeiD· 1 shared Wenke WangiD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 12 mutual co-author links

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3 shared papersCell Biology

Keiji ItohORCID

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4 papers

Recent·Most cited

Axin2L regulates planar cell polarity in Xenopus embryos

Velayudhan Satheeja Santhi, Keiji Itoh, Sergei Y. Sokol

This study shows Axin2L regulates planar cell polarity in Xenopus embryos by interacting with ADIP and affecting Vangl2 and ciliogenesis.

bioRxiv · Jul 30, 2026 · PreprintCell Biology

Planar polarization of endogenous ADIP during Xenopus neurulation

Velayudhan Satheeja Santhi, Keiji Itoh, Chih-Wen Chu, Dominique Alfandari, Sergei Y. Sokol

This study shows endogenous ADIP polarizes in response to mechanical forces during Xenopus neurulation, linking it to cytoskeletal networks and planar cell polarity.

Biology Open · Jan 28, 2026Peer-reviewedDevelopmental Biology

Mechanosensitive localization of Diversin highlights its function in vertebrate morphogenesis and planar cell polarity

Velayudhan Satheeja Santhi, Chih-Wen Chu, Keiji Itoh, Sergei Y. Sokol

This study shows Diversin localizes to cell junctions during Xenopus morphogenesis and responds to mechanical forces, influencing planar cell polarity and tissue closure.

Biology Open · Jul 28, 2025Peer-reviewedCell Biology

Adult-specific trimethylation of histone H3 lysine 4 is prone to dynamic changes with aging in C. elegans somatic cells

Mintie Pu, Minghui Wang, Wenke Wang, Velayudhan Satheeja Santhi, Siu Sylvia Lee

The paper investigates age-related changes in H3K4me3 in C. elegans, finding that adult-specific H3K4me3 regions correlate with gene expression changes during aging.

PLoS Genetics · Jun 18, 2018Peer-reviewedMolecular Biology