Siu Sylvia Lee

This study identifies new regulators of heat hormesis in C. elegans through transcriptomic and chromatin accessibility analysis, revealing tissue-specific responses and conserved factors involved in stress resilience and longevity.

The paper compares the effects of three different germline mutations on longevity and fat metabolism in C. elegans, finding distinct physiological outcomes.

This paper identifies NHR-49 as a regulator of oocyte activation and ovulation in C. elegans, linking fertility, resource allocation, and longevity through its role in controlling GSA-1 expression.

This study identifies SET-26 and HCF-1 as factors that antagonize HDA-1 to regulate gene expression and longevity in C. elegans.

This study identifies sex-specific metabolomic differences in C. elegans, revealing sex-dependent metabolites and their biological roles.

This study identifies age-dependent changes in repressive histone marks and repetitive elements in C. elegans, revealing new heterochromatin domains linked to aging.

The paper investigates age-related changes in H3K4me3 in C. elegans, finding that adult-specific H3K4me3 regions correlate with gene expression changes during aging.