Author

A. Aria Tzika

Harvard UniversityORCID 0000-0002-9482-6297Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Arijit ChakrabortyiD· 2 shared Laurence G. RahmeiD· 2 shared Sujin Cha· 2 shared Vijay Kumar SinghiD· 2 shared Alexandra DimitriouiD· 1 shared Arunava Bandyopadhaya· 1 shared Claire de CrescenzoiD· 1 shared Filip KovačićiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Arijit ChakrabortyORCID

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2 papers

Recent·Most cited

ImmunologyeLifePeer-reviewedJun 12, 2024

The Bacterial Quorum-Sensing Signal 2-Aminoacetophenone Rewires Immune Cell Bioenergetics through the PGC-1α/ERRα Axis to Mediate Tolerance to Infection

Arijit Chakraborty, Arunava Bandyopadhaya, Vijay Kumar Singh…·Laurence G. Rahme

This study shows that the bacterial QS signal 2-AA modulates immune cell bioenergetics via the PGC-1α/ERRα axis, promoting immune tolerance and pathogen persistence.

13 citations

mouseproteomics

𝕏 PostBluesky

MicrobiologymBioPeer-reviewedJun 11, 2024

Skeletal Muscle Mitochondrial Dysfunction Mediated by Pseudomonas aeruginosa Quorum Sensing Transcription Factor MvfR: Reversing Effects with Anti-MvfR and Mitochondrial-Targeted Compounds

Shifu Aggarwal, Vijay Kumar Singh, Arijit Chakraborty…·Laurence G. Rahme

This study investigates how Pseudomonas aeruginosa's MvfR quorum sensing transcription factor disrupts mitochondrial function in skeletal muscle and shows that inhibiting MvfR or using mitochondrial-targeted compounds can reverse these effects.

6 citations

mouseATAC-seq

𝕏 PostBluesky