Arseniy A. Lobov

This study identifies a small molecule targeting PSME4, which stabilizes STAT1 and reprograms tumor inflammation, suppressing tumor growth by altering cytokine signaling.

This study identifies Pcbp1's role in enhancing amino acid metabolism during the naive-to-primed pluripotency transition, linking its deficiency to embryo growth arrest and reduced protein synthesis.

This study investigates the physiological impact of folded-state protein agglomerates in yeast, finding they do not disrupt proteostasis or cell fitness and show minimal effects on cellular processes.

The paper compares proteomic and transcriptomic profiles of valve interstitial cells and osteoblasts during osteogenic differentiation, identifying potential therapeutic targets for calcific aortic valve disease.

The paper identifies structural determinants of co-translational protein complex assembly and shows how intertwined subunits require synchronized proteostasis, with implications for protein stability and mRNA localization.