Author

Paul Fernyhough

St. Boniface HospitalORCID 0000-0002-9507-1201Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Shayan AmiriiD· 2 shared Anjaparavanda P. NareniD· 1 shared Asuka InoueiD· 1 shared Darrell R. Smith· 1 shared Henry A. DunniD· 1 shared Kavisha AroraiD· 1 shared Mohamad‐Reza AghanooriiD· 1 shared Nisha Singh· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Shayan AmiriORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

T2R14 mediated antimicrobial responses through interactions with CFTR

Tejas M. Gupte, Nisha Singh, Vikram Bhatia, Kavisha Arora, Shayan Amiri, Paul Fernyhough, Anjaparavanda P. Naren, Shyamala Dakshinamurti, Prashen Chelikani

The paper investigates the interaction between T2R14 and CFTR, showing agonist-dependent physical coupling and Gq signaling in response to microbial signals.

The FASEB Journal · May 29, 2026Peer-reviewedBiochemistry

Antimuscarinic drugs exert β-arrestin-biased agonism at the muscarinic acetylcholine type 1 receptor

Shayan Amiri, Mohamad‐Reza Aghanoori, Darrell R. Smith, T.M. Zaved Waise, Ying Lao, Asuka Inoue, René Peiman Zahedi, Henry A. Dunn, Paul Fernyhough

Antimuscarinic drugs act as β-arrestin-biased agonists via casein kinase 2 activation to promote ERK1/2 phosphorylation and neurite outgrowth.

bioRxiv · Apr 16, 2025 · PreprintPharmacology & Toxicology