Anjaparavanda P. Naren

The paper investigates the interaction between T2R14 and CFTR, showing agonist-dependent physical coupling and Gq signaling in response to microbial signals.

This study identifies LPCAT1 as a critical regulator of AT2 cell renewal and lipid metabolism in IPF, showing that reactivating LPCAT1 can mitigate lung fibrosis.

The paper identifies SCCPDH as an off-target of VX-445 using a photoaffinity ligand and chemoproteomics, showing metabolic dysregulation and potential clinical implications.

This study identifies CFTR-related defects in idiopathic pancreatitis and shows that ivacaftor can reverse these defects in patient-derived models.

The paper compares genetic and oral histories of four Indian populations, finding genetic similarity to other Indian groups but no evidence of additional non-local genetic sources.

The paper constructs a single-cell reference atlas for human and mouse lung tissues to improve cell type annotation and data integration.

The paper identifies PP-2, a src-kinase inhibitor, as a novel corrector for ΔF508-CFTR in cystic fibrosis through in silico screening and experimental validation.