Ying Lao

The paper uses Drosophila to model CK2 variants causing neurodevelopmental disorders, finding loss- and gain-of-function effects and Wnt/β-catenin-mediated phenotypes.

Antimuscarinic drugs act as β-arrestin-biased agonists via casein kinase 2 activation to promote ERK1/2 phosphorylation and neurite outgrowth.

This study identifies Prx as a multifunctional metabolic regulator in Streptococcus pyogenes that interacts with DNA-binding proteins and transcriptional regulators, contributing to phage genome maintenance and pathogenicity.

SysQuan uses SILAC mouse tissues as internal standards to enable affordable absolute quantitation of the human proteome, improving comparability across studies and laboratories.

The paper identifies novel proteins and pathways in skeletal muscle-derived extracellular vesicles following chronic contractile activity, suggesting their role in metabolic and anti-tumorigenic effects.