René Peiman Zahedi

The paper uses Drosophila to model CK2 variants causing neurodevelopmental disorders, finding loss- and gain-of-function effects and Wnt/β-catenin-mediated phenotypes.

Antimuscarinic drugs act as β-arrestin-biased agonists via casein kinase 2 activation to promote ERK1/2 phosphorylation and neurite outgrowth.

SysQuan uses SILAC mouse tissues as internal standards to enable affordable absolute quantitation of the human proteome, improving comparability across studies and laboratories.

The paper identifies novel proteins and pathways in skeletal muscle-derived extracellular vesicles following chronic contractile activity, suggesting their role in metabolic and anti-tumorigenic effects.

This study identifies proteomic changes in the human male olfactory bulb associated with depression, highlighting astrocytic dysfunction and species-specific differences in mouse models.

The paper introduces a method to isolate intact microvessels from frozen tissue and uses multi-omics to characterize the neurovascular unit.