Author

Ian Robert Humphreys

Cardiff UniversityORCID 0000-0002-9512-5337Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Mathew ClementiD· 2 shared Morgan Marsden· 2 shared Agnieszka Andres· 1 shared Anneliese O. SpeakiD· 1 shared Awen GallimoreiD· 1 shared Bushra Abu-HeliliD· 1 shared Carmen Ballesteros Reviriego· 1 shared Cordelia Brandt· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Mathew ClementORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

In vivo screening reveals new regulators of Natural Killer cell development and functional response to acute cytomegalovirus infection

Eleanor J. Pring, Simon Clare, Roseanna K. Hare, Sam Sheppard, Morgan Marsden, Mathew Clement, Lucy Chapman, Katherine Harcourt, Carmen Ballesteros Reviriego, Cordelia Brandt, Agnieszka Andres, Bushra Abu-Helil, V Iyer, Louise van der Weyden, Maria A Oliver, , Anneliese O. Speak

The paper identifies novel regulators of NK cell development and antiviral function through in vivo screening in mice, with relevance to human health.

bioRxiv · Mar 20, 2026 · PreprintImmunology

Cytomegalovirus-induced T cell responses accelerate Alzheimer's disease progression in mice

Morgan Marsden, James E. McLaren, Ryan J. Bevan, Daisy Penn-Ripley, Michelle S. Somerville, Sarah N. Lauder, Manon H Jones, Lila-Blythe Maros, Matthew R McGurk, Awen Gallimore, David A. Price, Kelly L. Miners, Kristin Ladell, Florian A. Siebzehnrübl, Timothy Hughes, , Mathew Clement

This study shows that MCMV infection accelerates AD-like features in mice, with T cell responses playing a key role in disease progression.

Brain · Jan 31, 2026Peer-reviewedImmunology