Astrocyte immunosuppressive activity in glioblastoma depends on ZEB1 and is counteracted by CXCL14
Mathew Clement, Alex Gibbs, Ayesha Begum…·Florian A. Siebzehnrübl
This study shows that ZEB1 in astrocytes suppresses glioblastoma immunity, and CXCL14 can counteract this effect to enhance T-cell activity and reduce tumor growth.