Mathew Clement

Astrocyte immunosuppressive activity in glioblastoma depends on ZEB1 and is counteracted by CXCL14

This study shows that ZEB1 in astrocytes suppresses glioblastoma immunity, and CXCL14 can counteract this effect to enhance T-cell activity and reduce tumor growth.

In vivo screening reveals new regulators of Natural Killer cell development and functional response to acute cytomegalovirus infection

The paper identifies novel regulators of NK cell development and antiviral function through in vivo screening in mice, with relevance to human health.

Cytomegalovirus-induced T cell responses accelerate Alzheimer's disease progression in mice

This study shows that MCMV infection accelerates AD-like features in mice, with T cell responses playing a key role in disease progression.