Cell BiologybioRxivPreprint
Cholesterol remodels the endoplasmic reticulum to control myofibroblastic CAF function
Srimayee Vaidyanathan, Nicole Laurencia Yuwono, Ellie T. Y. Mok…·Kristin Brown
This study shows that cholesterol biosynthesis is critical for myofibroblastic CAFs to remodel the extracellular matrix and promote tumor metastasis.
DOI 10.64898/2026.02.16.706237