Author

Peter Scheiffele

University of BaselORCID 0000-0002-9516-9399Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:differential expression· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Assay:electronic health records· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

Dietmar Schreiner· 3 shared Raul Ortiz· 2 shared Zeynep OkuriD· 2 shared Agata NowackaiD· 1 shared Ákos KulikiD· 1 shared Alexander HauptiD· 1 shared Aline Bréchet· 1 shared Ayumi Hayashi· 1 shared

Activity by Year

2018-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersNeuroscience

Dietmar Schreiner

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Ternary Neurexin-T178-PTPR complexes represent a presynaptic core-module of neuronal synapse organization

Spyros Thivaios, Jochen Schwenk, Aline Bréchet, Sami Boudkkazi, Nithya Sethumadhavan, Phil Henneken, Eriko Miura, Ayumi Hayashi, Maciej K. Kocylowski, Alexander Haupt, Debora Kaminski, Dietmar Schreiner, Agata Nowacka, Jean-Baptiste van den Broucke, Ákos Kulik, , Bernd Fakler

The paper identifies a presynaptic core-module composed of Neurexins, T178 tetraspanins, and PTPRs that organizes synaptic adhesion and signaling in the mammalian brain.

Nature Communications · Sep 5, 2026Peer-reviewedNeuroscience

Principles of NMDA receptor co-agonism at cortical fast-spiking GABAergic interneurons in the adolescent prefrontal cortex

Isis Nem de Oliveira Souza, Pierre Lecouflet, Zeynep Okur, Steeve Maldera, Brigitte Potier, Loredano Pollegioni, Peter Scheiffele, Jean‐Pierre Mothet

The paper investigates NMDA receptor co-agonism in adolescent prefrontal cortex fast-spiking GABAergic interneurons, revealing distinct co-agonist regulation at different synaptic locations.

bioRxiv · Sep 3, 2026 · PreprintNeuroscience

Dilated cardiomyopathy-associated RNA Binding Motif Protein 20 regulates long pre-mRNAs in neurons

Giulia Di Bartolomei, Raul Ortiz, Dietmar Schreiner, Susanne Falkner, Esther E. Creemers, Peter Scheiffele

This study identifies RBM20 as a neuronal RNA-binding protein that regulates long pre-mRNAs, impacting synaptic protein expression and linking heart disease risk to neuronal function.

eLife · Jan 12, 2026Peer-reviewedNeuroscience

Control of neuronal excitation-inhibition balance by BMP-SMAD1 signaling

Zeynep Okur, Nadia Schlauri, Vassilis Bitsikas, Myrto Panopoulou, Raul Ortiz, Michaela Schwaiger, Kajari Karmakar, Dietmar Schreiner, Peter Scheiffele

This study identifies BMP-SMAD1 signaling as a pathway that maintains cortical excitation-inhibition balance by regulating PV interneuron function and connectivity in adult mice.

Nature · Apr 17, 2024Peer-reviewedNeuroscience

Cue-specific remodeling of the neuronal transcriptome through intron retention programs

Maxime Mazille, Katarzyna Buczak, Peter Scheiffele, Oriane Mauger

The paper identifies cue-specific nuclear retention of intron-containing transcripts in neurons and shows how different stimuli mobilize distinct groups of these transcripts through signaling pathways.

The EMBO Journal · Sep 23, 2022Peer-reviewedNeuroscience

Neuronal signature of social novelty exploration in the VTA: implication for Autism Spectrum Disorder

Sebastiano Bariselli, Hanna Hörnberg, Clément Solié, Stefano Musardo, Laetitia Hatstatt-Burklé, Peter Scheiffele, Camilla Bellone

This study identifies a role for VTA dopamine neurons in social novelty exploration and links their dysfunction to ASD-like behaviors in mice.

Nature Communications · Aug 3, 2018Peer-reviewedNeuroscience