Katarzyna Buczak

The paper develops a computational method to deconvolve cell cycle-dependent protein dynamics from bulk proteomics data in budding yeast and identifies 563 proteins with such dynamics.

This study shows DSG3 modulates p38MAPK and ERK signaling through Piezo1 in keratinocytes under mechanical stress.

The paper identifies a stable metabolic-secretory defect in RA monocytes across activation states using multi-omics analysis, linking reduced glycosylation to disease mechanisms.

This study shows that reduced RyR1 in muscle spindles of mice with recessive Ryr1 mutations causes proprioception issues and scoliosis.

This paper develops an immunocapture method to isolate CD90+ stromal-derived EVs from arthritis synovial fluid and performs proteomic profiling to identify disease-relevant EV subpopulations and biomarkers.

This study genetically validates PfFKBP35 as a lethal target in Plasmodium falciparum, showing its role in ribosome homeostasis and revealing non-canonical modes of action for FK506.

The paper identifies cue-specific nuclear retention of intron-containing transcripts in neurons and shows how different stimuli mobilize distinct groups of these transcripts through signaling pathways.

The paper uses AI to create a dynamic model of the human nuclear pore complex, showing how the protein scaffold interacts with the nuclear envelope.