A Cre-dependent massively parallel reporter assay allows for cell-type specific assessment of the functional effects of non-coding elements in vivo
Tomás Lagunas, Stephen P. Plassmeyer, Anthony D. Fischer, Ryan Z. Friedman, Michael A. Rieger, Din Selmanovic, Simona Sarafinovska, Yvette K Sol, Michael J. Kasper, Stuart B. Fass, Alessandra F. Aguilar Lucero, Joon‐Yong An, Stephan Sanders, Barak A. Cohen, Joseph D. Dougherty
The paper develops a method to assess the functional effects of non-coding elements in specific cell types in vivo using a Cre-dependent MPRA approach.
Communications Biology · Nov 12, 2023Peer-reviewedGenetics