Author

Ruth T. Yu

Salk Institute for Biological StudiesORCID 0000-0002-9527-9627Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Andrew M. LowyiD· 1 shared Annette R. AtkinsiD· 1 shared Christopher LiddleiD· 1 shared Daniel Y. Cao· 1 shared Dannielle D. EngleiD· 1 shared Dylan C. NelsoniD· 1 shared Gabriela EstepaiD· 1 shared Gaoyang LiangiD· 1 shared

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2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Andrew M. LowyORCID

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1 paper

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedJun 25, 2026

HDAC Inhibition Sensitizes Pancreatic Tumors to DNA Damage by Global Redistribution of the Transcriptional Machinery

Gaoyang Liang, Hung V.‐T. Nguyen, Jonathan Zhu…·Ronald M. Evans

This study shows HDAC inhibition reduces DDR gene expression in pancreatic tumors by altering transcriptional machinery distribution, enhancing sensitivity to DNA damage, and introduces a nanoparticle delivery system to reduce toxicity.

DOI 10.1073/pnas.2536040123

humanDNA methylation

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