Author

Daniel Y. Cao

Salk Institute for Biological Studies

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Andrew M. LowyiD· 1 shared Annette R. AtkinsiD· 1 shared Christopher LiddleiD· 1 shared Dannielle D. EngleiD· 1 shared Dylan C. NelsoniD· 1 shared Gabriela EstepaiD· 1 shared Gaoyang LiangiD· 1 shared Hadiqa ZafariD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Andrew M. LowyORCID

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1 paper

Recent·Most cited

HDAC Inhibition Sensitizes Pancreatic Tumors to DNA Damage by Global Redistribution of the Transcriptional Machinery

Gaoyang Liang, Hung V.‐T. Nguyen, Jonathan Zhu, Hervé Tiriac, Hadiqa Zafar, Daniel Y. Cao, Gabriela Estepa, Dylan C. Nelson, Yang Dai, Tae Gyu Oh, Christopher Liddle, Ruth T. Yu, Tony R. Hunter, Dannielle D. Engle, Reuben J. Shaw, , Ronald M. Evans

This study shows HDAC inhibition reduces DDR gene expression in pancreatic tumors by altering transcriptional machinery distribution, enhancing sensitivity to DNA damage, and introduces a nanoparticle delivery system to reduce toxicity.

Proceedings of the National Academy of Sciences · Jun 25, 2026Peer-reviewedCancer Biology