Author

Anne Christin Machel

Goethe University FrankfurtORCID 0000-0002-9542-9541Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biophysics· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Assay:imaging· 1 Assay:protein structure· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Anamari Brdar· 1 shared Birgit Schäfer· 1 shared Büşra YükseliD· 1 shared Christian OsterburgiD· 1 shared Chrysa KapeniiD· 1 shared Dilyara Sabirova· 1 shared Flavio BekeiD· 1 shared Ivan ĐikićiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiophysics

Anamari Brdar

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologyScience ImmunologyPeer-reviewedJul 11, 2025

Hedgehog signaling controls cytotoxic T cell migration in the tumour microenvironment.

Chrysa Kapeni, Louise M. O’Brien, Dilyara Sabirova…·Maike de la Roche

This study shows that Hedgehog signaling via Smo regulates CD8 T cell migration into tumors, explaining why Hh inhibitors fail in solid cancers.

2 citations

mouseexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivOct 2, 2024

p53 isoforms have a high aggregation propensity, interact with chaperones and lack binding to p53 interaction partners

Anamari Brdar, Christian Osterburg, Philipp Münick…·Volker Dötsch

5 citations

humanprotein structure

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 30, 2018

Resolving Tumour Clonal Heterogeneity and Spatial Complexity using Nuclear Tandem Epitope Protein (nTEP) Barcoding

Michael B. Gill, Simon Koplev, Anne C. Machel, Martin L. Miller

This paper introduces nTEP barcoding to spatially resolve tumour clones and their interactions with the microenvironment using multiplexed antibody imaging.

DOI 10.1101/456855

𝕏 PostBluesky