Author

Pekka L. J. Virtanen

University of HelsinkiORCID 0000-0002-9547-4940Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Anastasia LudwigiD· 1 shared Claudio RiveraiD· 1 shared Heikki TanilaiD· 1 shared Hennariikka Koivisto· 1 shared Hiramani DhunganaiD· 1 shared Ida Hyötyläinen· 1 shared Iiris HovattaiD· 1 shared Ilkka Ojansuu· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Anastasia LudwigORCID

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1 paper

Recent·Most cited

Patient iPSC-astrocytes show transcriptional and functional dysregulation in schizophrenia

Marja Koskuvi, Šárka Lehtonen, Kalevi Trontti, Meike Hedwig Keuters, Ying Chieh Wu, Hennariikka Koivisto, Anastasia Ludwig, L. M. Plotnikova, Pekka L. J. Virtanen, Noora Räsänen, Satu Kaipainen, Ida Hyötyläinen, Hiramani Dhungana, Raisa Giniatullina, Ilkka Ojansuu, , Jari Koıstınaho

The paper shows that astrocytes from schizophrenia patients exhibit transcriptional and functional changes, including inflammation and synaptic pathway alterations, which are partially reversible with clozapine treatment.

bioRxiv · Oct 23, 2020 · PreprintNeuroscience