Diabetic phenotype in mouse and humans with β-amyloid pathology reduces the number of microglia around β-amyloid plaques
Teemu Natunen, Henna Martiskainen, Mikael Marttinen, Sami Gabbouj, Hennariikka Koivisto, Susanna Kemppainen, Satu Kaipainen, Mari Takalo, Helena Svobodová, Luukas Leppänen, Benjam Kemiläinen, Simo Ryhänen, Teemu Kuulasmaa, Eija Rahunen, Sisko Juutinen, , Mikko Hiltunen
This study shows that a diabetic phenotype in mice and humans reduces microglial response to β-amyloid plaques, linking T2D and AD pathologies.
Molecular Neurodegeneration · Nov 9, 2020Peer-reviewedNeuroscience