Avencia Sánchez-Mejías

CRISPR-Analytics provides a tool and pipeline for accurate gene editing analysis and simulation, improving precision in experimental design and results interpretation.

This study enhances homology-directed repair (HDR) efficiency by using PRDM9-Cas9 fusion with CtIP, validated through reporter systems for small and longer edits.

INSERT-seq uses long-read sequencing to accurately detect DNA integration events, improving detection in repetitive regions.