Author

Isabel Turpín

Universitat Pompeu Fabra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1 Genomics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Sandra AcostaiD· 4 shared Andrea Martí-SarriasiD· 2 shared Adriana Modrego· 1 shared Alba Ortega-GascóiD· 1 shared Alba Segarra‐CasasiD· 1 shared Ángel Bayón-GiliD· 1 shared Anna-Christina HaebiD· 1 shared Arcadi NavarroiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersCell Biology

Sandra AcostaORCID

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Author profile →

4 papers

Recent·Most cited

MIF overexpression upon SARS-CoV-2 infection induces neural regeneration in human-derived brain organoids

Andrea Martí-Sarrias, Maria Carmen Puertas, Isabel Turpín, Lidia Garrido-Sanz, Ángel Bayón-Gil, Patricia Resa‐Infante, Jakub Chojnacki, Maria C. García-Guerrero, Víctor Urrea, Ramón Lorenzo-Redondo, Sandra Acosta, Javier Martínez‐Picado

This study shows that MIF overexpression after SARS-CoV-2 infection promotes neural regeneration in human brain organoids through EGFR signaling and self-upregulation.

bioRxiv · Feb 16, 2026 · PreprintCell Biology

Variability vs Phenotype: multimodal analysis of Dravet Syndrome Brain Organoids powered by Deep Learning

Isabel Turpín, Adriana Modrego, Andrea Martí-Sarrias, Laura García‐González, Alba Ortega-Gascó, Anna-Christina Haeb, Ruth I. Pareja, Jordi Soriano, Nuria Ruíz, Irene Peñuelas‐Haro, Elisa Espinet, Arcadi Navarro, Daniel Tornero, Óscar Lao, Sandra Acosta

The paper develops ImPheNet, a deep learning tool to classify phenotypes and assess drug toxicity in Dravet Syndrome brain organoids using live imaging data.

iScience · Oct 23, 2025Peer-reviewedDevelopmental Biology

Synergic homology directed recombination by PRDM9 meiotic factor

Marta Sanvicente-García, Lourdes González-Bermúdez, Isabel Turpín, Laura Batlle‐Morera, Sandra Acosta, Marc Güell, Avencia Sánchez-Mejías

This study enhances homology-directed repair (HDR) efficiency by using PRDM9-Cas9 fusion with CtIP, validated through reporter systems for small and longer edits.

bioRxiv · Dec 5, 2022 · PreprintSynthetic Biology

Intronic enhancers regulate the expression of genes involved in tissue-specific functions and homeostasis

Beatrice Borsari, Pablo Villegas-Mirón, Sílvia Pérez-Lluch, Isabel Turpín, Hafid Laayouni, Alba Segarra‐Casas, Jaume Bertranpetit, Roderic Guigó, Sandra Acosta

The paper shows that tissue-specific enhancers are mostly intronic and regulate genes involved in tissue-specific functions, while housekeeping genes are controlled by intergenic enhancers.

Genome Research · Aug 1, 2021Peer-reviewedGenomics